P-hydroxyphenylacetate

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August undefined, 2024

WebHpaR is a transcription regulator in the MarR family that controls the expression of the gene cluster responsible for conversion of p-hydroxyphenylacetate to pyruvate and succinate … WebA novel glycyl radical enzyme catalysing the formation of p-cresol Eur. J. Biochem. 268 1363-1372 2001 Clostridioides difficile ... Zauner, S.; Andrei-Selmer, L.C.; Selmer, T. Subunit composition of the glycyl radical enzyme p-hydroxyphenylacetate decarboxylase. A small subunit, HpdC, is essential for catalytic activity Eur. J. Biochem. 271 ...

Subunit composition of the glycyl radical enzyme p-hydroxyphenylacetate …

WebApr 27, 2024 · Abstract. The glycyl radical enzymes (GREs) p -hydroxyphenylacetate (HPA) decarboxylase (HPAD), indoleacetate decarboxylase, and phenylacetate decarboxylase … Webp-Hydroxyphenylacetate decarboxylase from Clostridium difficile catalyses the decarboxylation of p-hydroxyphenylacetate to yield the cytotoxic compound p-cresol. The three genes encoding two subunits of the glycyl-radical enzyme and the activating enzyme have been cloned and expressed in Escherichia coli. new everydrop water filter

A Single-Site Mutation at Ser146 Expands the Reactivity of the ...

WebThere are two known types of microbial two-component flavin-dependent monooxygenases that catalyze oxygenation of p-hydroxyphenylacetate (HPA), and they are distinguished by having structurally distinct reductases and oxygenases. This paper presents a detailed analysis of the properties of the enzyme from Pseudomonas aeruginosa, an example of ... WebOct 1, 2024 · P-Hydroxyphenyllactate is a marker of cell turnover. It is also a metabolite in tyrosine degradation and may be useful for studying disorders of tyrosine metabolism, … WebDec 7, 2012 · Metabolic profiling revealed acetate, alanine, butyrate, isobutyrate, p-cresol and p-hydroxyphenylacetate were the main metabolites responsible for differentiating the parent strain C. difficile (630Δerm) from a p-cresol deficient mutant. p-cresol mutant displays a fitness defect in a mouse relapse model of C. difficile infection. Analysis of ... new every mind matters campaign

Enzymes in the p-hydroxyphenylacetate degradation …

WebOct 5, 2024 · Aldolases catalyze the reversible reactions of aldol condensation and cleavage and have strong potential for the synthesis of chiral compounds, widely used in pharmaceuticals. Here, we investigated a new Class II metal aldolase from the p -hydroxyphenylacetate degradation pathway in Acinetobacter baumannii, 4-hydroxy … WebDec 1, 2016 · 1. Introduction. p-Hydroxyphenylacetate (HPA) is an aromatic compound that is prevalent throughout nature.It can be derived from the biodegradation of lignin, the third most abundant biomass next to cellulose and hemi-cellulose, or from the degradation of man-made industrial compounds such as p-chlorophenylacetate .HPA is also found as a … new everyman folk clubWebJun 27, 2007 · p-Hydroxyphenylacetate hydroxylase (HPAH) from Acinetobacter baumannii catalyzes the hydroxylation of p-hydroxyphenylacetate (HPA) to form 3,4-dihydroxyphenylacetate (DHPA). HPAH is composed of two proteins: a flavin mononucleotide (FMN) reductase (C1) and an oxygenase (C2). C1 catalyzes the reduction … new every morning coolidge

"Web4-Hydroxyphenylacetic acid is obtained by reducing 4-hydroxymandelic acid with elemental phosphorus and iodine. [3] Uses [ edit] In industry, 4-hydroxyphenylacetic acid is an … " - P-hydroxyphenylacetate

P-hydroxyphenylacetate

WebMar 23, 2024 · Hydrogenation of methyl p-hydroxyphenylacetate has been used for the synthesis of p-hydroxyphenyl ethanol. The reaction was catalyzed by CuiZrj-x%(mass fra Efficient Synthesis of p-Hydroxyphenyl Ethanol from Hydrogenation of Methyl p-Hydroxyphenylacetate with CNTs-promoted Cu-Zr Catalyst SpringerLink WebJun 27, 2007 · p-Hydroxyphenylacetate hydroxylase (HPAH) from Acinetobacter baumannii catalyzes the hydroxylation of p-hydroxyphenylacetate (HPA) to form 3,4 …

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Web4-Hydroxyphenylacetate decarboxylase (4Hpad) is an Fe/S cluster containing glycyl radical enzyme (GRE), which catalyses the last step of tyrosine fermentation in clostridia, generating the bacteriostatic p-cresol. The respective activating enzyme (4Hpad-AE) displays two cysteine-rich motifs in addition to the classical S-adenosylmethionine (SAM ... Webp-hydroxyphenylacetate: ( hī-droks'ē-fen'il-as'ĕ-tāt ), A minor side product of l -tyrosine degradation that is elevated in the urine in cases of neonatal tyrosinemia and in type II tyrosinemia.

WebApr 15, 2024 · p-hydroxyphenylacetate 3-hydroxylase from Acinetobacter baumannii catalyzes the hydroxylation of p-hydroxyphenylacetate (HPA) to yield 3,4-dihydroxyphenylacetate (DHPA).In this study, we investigated whether variants of the oxygenase component (C 2) could catalyze hydroxylation of 4-hydroxyphenylethylamines … WebDec 1, 2016 · p-Hydroxyphenylacetate (HPA) is an aromatic compound that is prevalent throughout nature. It can be derived from the biodegradation of lignin, the third most …

WebDec 25, 1992 · p-Hydroxyphenylacetate-3-hydroxylase, an inducible enzyme isolated from the soil bacterium Pseudomonas putida, catalyzes the conversion of p-hydroxyphenylacetate to 3,4-dihydroxyphenylacetate. The enzyme requires two protein components: a flavoprotein and a colorless protein referred to as the coupling protein. … WebAldrich-H50004; 4-Hydroxyphenylacetic acid 0.98; CAS Number: 156-38-7; Linear Formula: HOC6H4CH2CO2H; find related products, papers, technical documents, MSDS & more at …

WebThe oxygenase component (C2) of p-hydroxyphenylacetate (4-HPA) 3-hydroxylase (HPAH) from Acinetobacter baumannii catalyzes the hydroxylation of various phenolic acids. In this report, we found that substitution of a residue close to the phenolic group binding site to yield the S146A variant resulted in an enzyme that is more effective than the wild-type in …

Webp-Hydroxyphenylacetic acid, also known as 4-hydroxybenzeneacetate, is classified as a member of the 1-hydroxy-2-unsubstituted benzenoids. 1-Hydroxy-2-unsubstituted benzenoids are phenols that are unsubstituted at the 2-position. p-Hydroxyphenylacetic acid is considered to be slightly soluble (in water) and acidic. new every morning bibleWebDec 30, 1997 · Phenylacetic acid and methyl p-hydroxyphenylacetate were isolated from culture filtrates not containing fusaric acid and identified on the basis of 1H and 13C NMR spectra as the major secondary metabolites. Phenylacetic acid, and to a lower extent methyl p-hydroxyphenylacetate, were phytotoxic to pea, rapeseed, lettuce, garden cress and … new every morning is thy love lyricsWeb英文同义词: METHYL 4-HYDROXYPHENYLACETATE;METHYL P-HYDROXYPHENYL ACETATE;4-HYDROXYPHENYLACETIC ACID METHYL ESTER;4-hydroxy-benzeneaceticacimethylester;Acetic acid, (p-hydroxyphenyl)-, methyl ester;p-Hydroxyphenylacetic acid methyl ester;Methyl 4-hydroxyphenylacetate 99%;Methyl 4 … new every morning susan coolidgeWebp-hydroxyphenylacetate: ( hī-droks'ē-fen'il-as'ĕ-tāt ), A minor side product of l -tyrosine degradation that is elevated in the urine in cases of neonatal tyrosinemia and in type II … new every morning kjvWebJun 23, 2006 · p -Hydroxyphenylacetate hydroxylase (HPAH) from Acinetobacter baumannii catalyzes the hydroxylation of p -hydroxyphenylacetate (HPA) to form 3,4-dihydroxyphenylacetate (DHPA). The enzyme system is composed of two proteins: an FMN reductase (C) and an oxygenase that uses FMNH – (C ). new every morning lindell cooleyWebFeb 20, 2024 · Adoxosidic Acid 10-p-Hydroxyphenylacetate (CHEMBL - CHEMBL4209626) Sorafenib (CHEMBL - CHEMBL1336) Alphitolic acid (CHEMBL - CHEMBL4207806) Similar Articles . To arrive at the top five similar articles we use a word-weighted algorithm to compare words from the Title and Abstract of each citation. interruptores thqbWebp-Hydroxyphenylacetate decarboxylase from Clostridium difficile catalyses the decarboxylation of p-hydroxyphenylacetate to yield the cytotoxic compound p-cresol. The … new every morning daylilies